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Animal Testing Alternatives

S. 640/H. 989: An Act promoting humane cosmetics and other household products by limiting the use of animal testing

MSPCA Position: Support
Sponsors: Senator Mark Montigny and Representative Jack Patrick Lewis
Status: Referred to Joint Committee on Environment and Natural Resources


Every year, tens of thousands of animals suffer and die in product testing in the U.S. In common toxicity testing, harsh chemicals are applied to an animal’s skin, forced down their throat or into their lungs, and dripped into their eyes. Pain relief may be withheld. This legislation would require manufacturers and contract testing facilities to use non-animal testing methods instead of traditional animal tests when a valid alternative exists. The bills apply to products such as cosmetics, household cleaners, and industrial chemicals, like those in paint; they do not apply to testing done for medical research, including testing of drugs or medical devices. Learn more about product safety testing, alternatives to using animals in science, and also our other legislation that would ban the sale of most cosmetics newly tested on animals.

21st century science is rapidly moving away from outdated animal tests as many faster, less expensive, and more human-relevant alternative methods have become available, including artificial human tissue, organs-on-chips, and sophisticated computer programs. This shift toward non-animal methods builds on recommendations of the U.S. National Research Council’s 2007 report, Toxicity Testing in the 21st Century, which lays the groundwork for a “paradigm shift” in safety testing. It also conforms to the bipartisan-supported 2016 Frank R. Lautenberg Chemical Safety of the 21st Century Act, which requires the EPA to minimize animal testing.

In 2019, the U.S. Environmental Protection Agency (EPA) emphasized that they remained committed to ending the use of mammals in science and testing, both in their own studies and in funding requirements. Additionally, in February 2020, the EPA issued final guidance that reduces unnecessary testing on birds in the pesticide registration review process, which is expected to save 720 test animals annually. And in July 2020, the EPA released guidance that reduces unnecessary testing on fish in the pesticide registration process, expected to save 240 test animals annually.

Non-animal test methods save time and money. Non-animal alternatives provide more efficient as well as more effective chemical safety assessment. Human cell-based tests and advanced computer models, for example, deliver human-relevant results in hours or days, unlike some animal tests that can take months or years.

Animal tests do not ensure human safety. No longer considered the gold standard of product testing, animal models carry serious scientific limitations. Different species can respond differently when exposed to the same chemicals, and even different sexes or sub-species can respond differently. Consequently, results from animal tests may not be relevant to humans, thereby under- or over-estimating health hazards. Alternative methods based on human biology are much more likely to provide results predictive of human responses.

Animals suffer in product tests. Every year, tens of thousands of animals suffer and die in product testing in the U.S. Thousands may be used for a single test, and they often suffer for months or years before being euthanized. The situation is all the more urgent given that mice, rats, and birds who have been purpose-bred for research make up roughly 95% of animals used in research and testing, and yet they are excluded from  the protection of the Animal Welfare Act.

Massachusetts is a scientific and technological leader in non-animal alternatives. Massachusetts consistently ranks as a top research dollars recipient of the National Institutes of Health (NIH), which, in its 2016-2020 strategic plan, stresses the importance of replacing animal testing models with scientifically superior alternative methods. The NIH in fact states in a 2021 report that, “High rates of failure in the development of novel therapeutics whose progression to human clinical trials was supported by animal studies has prompted concern that animal models of the human condition are more imperfect than presumed.” As a top grant recipient, the Commonwealth has a vested interest in aligning its scientific goals and practices with those of the NIH.

California, New Jersey, New York, and Virginia have all passed legislation similar to this bill. Additionally, twelve states have passed laws to prohibit the sale of cosmetics newly tested on animals: California, Hawaii, Illinois, Louisiana, Maine, Maryland, Nevada, New Jersey, New York, Oregon, Virginia and Washington. It is time for Massachusetts to pass this legislation and join in the adoption of 21st century approaches to product safety testing.

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Co-Sponsors

Updated 5/15/2025

State Senators:

Name District/Address
Mark C. Montigny Second Bristol and Plymouth
John F. Keenan Norfolk and Plymouth
Joanne M. Comerford Hampshire, Franklin and Worcester
Michael O. Moore Second Worcester
James B. Eldridge Middlesex and Worcester
Adam Gómez Hampden
Bruce E. Tarr First Essex and Middlesex
Paul W. Mark Berkshire, Hampden, Franklin and Hampshire
Patrick M. O’Connor First Plymouth and Norfolk
Lydia Edwards Third Suffolk
John J. Cronin Worcester and Middlesex
Paul R. Feeney Bristol and Norfolk
Robyn K. Kennedy First Worcester
Patricia D. Jehlen Second Middlesex

State Representatives:

Name District/Address
Jack Patrick Lewis 7th Middlesex
Angelo J. Puppolo, Jr. 12th Hampden
Lindsay N. Sabadosa 1st Hampshire
Brian W. Murray 10th Worcester
Samantha Montaño 15th Suffolk
Christopher Hendricks 11th Bristol
Marcus S. Vaughn 9th Norfolk
Brian M. Ashe 2nd Hampden
Rodney M. Elliott 16th Middlesex
Mike Connolly 26th Middlesex
James K. Hawkins 2nd Bristol
Tara T. Hong 18th Middlesex
Manny Cruz 7th Essex
Christine P. Barber 34th Middlesex
James C. Arena-DeRosa 8th Middlesex
Kimberly N. Ferguson 1st Worcester
Vanna Howard 17th Middlesex
Tram T. Nguyen 18th Essex
James Arciero 2nd Middlesex
Patrick Joseph Kearney 4th Plymouth
David Henry Argosky LeBoeuf 17th Worcester
William C. Galvin 6th Norfolk
Thomas M. Stanley 9th Middlesex
Adam J. Scanlon 14th Bristol
Adrianne Pusateri Ramos 14th Essex
John J. Marsi 6th Worcester
Steven George Xiarhos 5th Barnstable
Carmine Lawrence Gentile 13th Middlesex
Adrian C. Madaro 1st Suffolk
Sean Reid 11th Essex
David M. Rogers 24th Middlesex
Danillo A. Sena 37th Middlesex
David T. Vieira 3rd Barnstable
Natalie M. Higgins 4th Worcester
John Barrett, III 1st Berkshire
Steven Owens 29th Middlesex
Michael P. Kushmerek 3rd Worcester
Bradley H. Jones, Jr. 20th Middlesex
Margaret R. Scarsdale 1st Middlesex
Sean Garballey 23rd Middlesex
Michelle M. DuBois 10th Plymouth
Colleen M. Garry 36th Middlesex
Tommy Vitolo 15th Norfolk
William F. MacGregor 10th Suffolk
Marjorie C. Decker 25th Middlesex