Synovetin OA® is a minimally-invasive treatment that targets dog arthritis at its source for up to 1 full year of pain relief.

It’s a simple, safe, fast arthritis injection, after which your dog can go home with you the same day.

Synovetin OA is a completely different arthritis treatment that acts on the driver of the disease itself—inflammation—not just symptoms. That means pain relief today that lasts up to 1 full year AND the potential to prevent future pain by delaying the joint damage that’s caused by inflammation as it gets worse over time.^1-3

Synovetin OA is designed to target the inflammation inside the joint that can result in pain and lameness.

Arthritis is the result of long-term inflammation inside your dog’s joints that can begin even in young, active dogs. If that inflammation is not addressed, the arthritis will likely get worse over time. It’s important to reduce the inflammation that drives the disease as early as possible to help prevent joint destruction and help your dog live an active, playful life.

Some drugs mask pain signals but don’t address the inflammation that’s damaging the joint. And, if only the pain is managed but not the inflammation that’s causing it, arthritis can progress to the point where those pain relievers no longer work.

Synovetin OA is completely different. It goes to work, exactly where it’s needed to help restore the health of the joint at any stage of arthritis, although sooner is better than later. And, because it’s dosed directly into the arthritic joint, it doesn’t spread throughout your dog’s entire body like medications do, which can cause side effects.⁴

How it Works

Synovetin OA is a targeted treatment, offered through Angell’s Surgery service, that uses microscopic radiotherapeutic particles to reduce inflammation inside the joint. Once there, it targets and safely eliminates harmful inflammatory cells that cause arthritis pain, destroy cartilage, and cause the disease to worsen. This same treatment approach has been safely and effectively used for decades to treat arthritis in people in countries around the world.

Clinical Studies

Clinical Studies with Synovetin OA show 92% treatment success for early-mid stage arthritis and 71% treatment success for late-stage arthritis.¹

Important Information About Synovetin OA

Studied in canine elbows, Synovetin OA is given by authorized veterinarians. Temporary discomfort in treated joints may occur. Talk to a treating veterinarian for more information.

Synovetin OA at Angell

To arrange Synovetin OA treatment at Angell by an authorized veterinarian, please contact Angell’s Surgery service at 617-541-5048 or email synovetin@angell.org for more information.

References

Information is sourced from activedognow.com and the following references.

1. Aulakh KS, Lopez MJ, Hudson C, et al. Prospective Clinical Evaluation of Intra-Articular Injection of Tin-117m (^117mSn) Radiosynoviorthesis Agent for Management of Naturally Occurring Elbow Osteoarthritis in Dogs: A Pilot Study. Vet Med (Auckl). 2021. Jun 4;12:117-128. doi: 10.2147/VMRR.S295309. PMID: 34113552; PMCID: PMC8187093.
2. Donecker J, Fabiani M, Gaschen L, Aulakh KS. Treatment response in dogs with naturally occurring grade 3 elbow osteoarthritis following intra-articular injection of 117mSn (tin) colloid. PLoS One.2021. Jul 19;16(7):e0254613. doi: 10.1371/journal.pone.0254613. PMID: 34280212; PMCID: PMC8289027.
3. Donecker J, Lattimer JC, Gaschen L, Aulakh KS. Safety and Clinical Response Following a Repeat Intraarticular Injection of Tin-117m (^117mSn) Colloid in Dogs with Elbow Osteoarthritis. Vet Med (Auckl).2021. Dec 17;12:325-335. doi: 10.2147/VMRR.S345144. PMID: 34950571; PMCID: PMC8691448.
4. Lattimer JC, Selting KA, Lunceford JM, et al. Intraarticular injection of a Tin-117 m radiosynoviorthesis agent in normal canine elbows causes no adverse effects. Vet Radiol Ultrasound.2019. Sep;60(5):567-574. doi: 10.1111/vru.12757. Epub 2019 Jun 2. PMID: 31155782.